TABLE 3.
Kinetic parameters of TRL apoB-48 and VLDL, IDL, and LDL apoB-100 of the subjects (n = 30) at the end of each diet1
| SFAs | ω-6 PUFAs | %Δ | P 2 | |
|---|---|---|---|---|
| TRL apoB-48 | ||||
| PS, mg | 55.0 ± 32.1 | 57.4 ± 28.6 | +4.2 ± 14.2 | 0.7 |
| FCR, pools/d | 8.38 ± 4.47 | 8.07 ± 3.19 | –3.8 ± 11.9 | 0.7 |
| PR, mg · kg−1 · d−1 | 4.05 ± 2.42 | 4.10 ± 1.44 | +1.2 ± 12.6 | 0.9 |
| VLDL apoB-100 | ||||
| PS, mg | 596 ± 378 | 632 ± 423 | +6.0 ± 15.3 | 0.5 |
| FCR, pools/d | 7.79 ± 4.07 | 7.65 ± 2.62 | –1.8 ± 11.3 | 0.9 |
| PR, mg · kg−1 · d−1 | 39.4 ± 13.5 | 42.7 ± 13.0 | +8.4 ± 8.6 | 0.2 |
| Direct catabolic | 18.1 ± 23.4 | 16.8 ± 20.8 | –7.2 ± 31.6 | 0.7 |
| rate, % | ||||
| IDL apoB-100 | ||||
| PS, mg | 124.9 ± 47.3 | 118.8 ± 49.1 | –4.9 ± 9.9 | 0.2 |
| FCR, pools/d | 20.5 ± 21.6 | 19.5 ± 9.4 | –4.9 ± 21.0 | 0.7 |
| PR, mg · kg−1 · d−1 | 23.3 ± 22.2 | 22.1 ± 9.8 | –5.2 ± 18.9 | 0.7 |
| Direct catabolic | 73.4 ± 39.9 | 80.4 ± 35.4 | +9.5 ± 13.3 | 0.3 |
| rate, % | ||||
| LDL apoB-100 | ||||
| PS, mg | 5126 ± 2215 | 4726 ± 2261 | –7.8 ± 11.3 | 0.005 |
| FCR, pools/d | 0.37 ± 0.12 | 0.37 ± 0.14 | +0.0 ± 8.1 | 0.9 |
| PR, mg · kg−1 · d−1 | 17.9 ± 7.3 | 16.1 ± 7.2 | –10.1 ± 10.6 | 0.003 |
| Conversion rate | ||||
| VLDL to IDL, % | 48.5 ± 18.9 | 50.2 ± 18.1 | +3.5 ± 9.8 | 0.6 |
| VLDL to LDL, % | 33.5 ± 16.3 | 33.0 ± 16.6 | –1.5 ± 12.7 | 0.9 |
| IDL to LDL, % | 26.5 ± 39.9 | 19.5 ± 35.4 | –26.4 ± 36.8 | 0.3 |
1
Diet-specific data are presented as means ± SDs. Differences between diets are presented as means ± SEMs. apo, apolipoprotein; FCR, fractional catabolic rate; IDL, intermediate-density lipoprotein; PR, production rate; PS, pool size; TRL, triglyceride-rich lipoprotein; Δ, change.
2
P values were calculated with mixed models for repeated measures with subjects as a random effect.