. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: Food Chem Toxicol. 2018 Apr 17;116(Pt B):227–232. doi: 10.1016/j.fct.2018.04.027

Table 2.

Serum concentrations of ZEA and its metabolites in adult women¹–²

Metabolites	Free (ng/mL)			Conjugated (ng/mL)
	Detection	All values	Values > LOD	Detection	All Values	Values > LOD
zearalenone (ZEA)	85.4%	0.026 ± 0.022	0.087 ± 0.020	100%	0.603 ± 0.436	0.641± 0.419
α-zearalenol	6.3%	0.001 ± 0.006	none	62.5%	0.208 ± 0.321	0.444 ± 0.350
β-zearalenol	35.4%	0.011 ± 0.021	0.089 ± 0.017	39.6%	0.053 ± 0.161	0.231 ± 0.205
zeranol	16.7%	0.005 ± 0.011	None	75.0%	0.181 ± 0.218	0.300 ± 0.216
zearalanone	31.3%	0.022 ± 0.043	0.102 ± 0.039	93.8%	0.174 ± 0.128	0.203 ± 0.119
taleranol	8.3%	0.001 ± 0.004	None	16.7%	0.020 ± 0.060	0.176 ± 0.089
Total ZEA metabolites	97.9%	0.066 ± 0.067	0.123 ± 0.077	100%	1.264 ± 0.884	1.298 ± 0.867

Values are mean ± SD (n=48). Zero value is used for non-detectable samples. The total metabolites concentration is equal to the sum of zearalenone, zeranol, taleranol α-zearalenol, β-zearalenol, zearalanone concentrations. Detection indicates the percent of samples with values above zero.

The number of samples with values > LOD (0.07) for free and conjugated are as follows: ZEA (3, 45), zeranol (0, 28), taleranol (0, 5) α-zearalenol (0, 22), β-zearalenol (2, 16), zearalanone (9, 40), ZEA metabolites (11, 46).