TABLE 4.

Characteristics of ZIKV and DENV LFn fusion proteins during convalescence

Subject	HIV status	Flavivirus immune status	Infection PBMC collection yr	No. of SFC/106 PBMC
				IFN-γ+		TNF-α+
				LFn ZIKV or DENV NS3-P	LFn ZIKV or DENV NS3-H	LFn ZIKV or DENV NS3-P	LFn ZIKV or DENV NS3-H
ZIKV
1	Negative	No	1998	57	188	55	92
2	Negative	Yes	1999	182	466	63	205
3	HIV dual	No	2000	105	220	78	182
4	Negative	No	2000	122	213	99	123
5	HIV-1	No	2000	141	182	132	110
6	Negative	Yes	2001	112	345	102	298
7	Negative	No	2001	134	287	152	133
8	Negative	Yes	2002	175	324	110	270
9	Negative	No	2003	113	198	72	98
10	Negative	Yes	2003	218	348	76	215
11	Negative	Yes	2003	110	388	88	232
12	Negative	No	NA
13	HIV dual	Yes	NA
14	Negative	No	NA
DENV
1	Negative	No	1999	172	335	186	205
2	HIV-2	No	1999	165	290	87	153
3	Negative	No	2000	32	20	38	22
4	Negative	No	2000	186	312	235	228
5	Negative	Yes	2000	183	374	125	266
6	Negative	Yes	2001	188	490	190	288
7	Negative	Yes	2002	312	508	220	373
8	HIV-1	No	2002	160	200	108	290
9	HIV-1	Yes	NA
10	Negative	No	NA
11	Negative	Yes	NA