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VACV proteins with roles in uncoating and DNA synthesis
| Protein, Cop (WR)a | Size (kDa) | Expression | Viruses with homologs | Essential | Domains | Ubiquitin/proteasome interaction |
|---|---|---|---|---|---|---|
| D5 (110) | 90 | Early | All poxviruses | Yes | Helicase, primase | ? |
| B18 (199) | 68 | Early | Orthopoxviruses | No | Ankyrin repeats, F box | Yes |
| C5 (023) | 25 | Early | Orthopoxviruses | No | BTB, Kelch | Yes |
| M2 (031) | 25 | Early | Orthopoxviruses | No | Signal peptide, PIE | ? |
Cop, VACV Copenhagen nomenclature; WR, WR nomenclature.
