TABLE 1.
CMV vaccines currently under development
Vaccine | Developer | Antigena |
Reference no. | ||
---|---|---|---|---|---|
gB | Pentamer | pp65 | |||
Adenovirus vector | Queensland Institute | X | 73 | ||
Alphavirus replicons | GSK | X | X | 74 | |
Canarypox vector | Sanofi | X | 75 | ||
Dense bodies | Vaccine Project Management, Serum Institute, India | X | X | X | 76 |
DNA plasmids | Astellas, Inovio | X | X | 77, 78 | |
Lentivirus particles | Variations Bio | X | X | 79 | |
Live attenuated | Medimmune | X | X | 80, 81 | |
Live replication-defective | Merck | X | X | X | 82 |
LCMV vector | Hookipa | X | X | 83 | |
mRNA | GSK, Moderna | X | X | 84 | |
MVA vector | City of Hope | X | X | 85 | |
Peptides | City of Hope, University of Heidelberg | X | 86 | ||
Soluble pentamer | Humabs, Redbiotech GSK | X | 87 | ||
Subunit gB | Sanofi, GSK | X | 8, 9, 88 | ||
VSV vector | Yale | X | 89 |
LCMV, lymphocytic choriomeningitis virus; VSV, vesicular stomatitis virus. An “X” indicates that the antigen is included in the vaccine candidate.