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Illustration of a designer immunotoxin produced in the C. reinhardtii chloroplast showing the multi-domain structure. The human CD22-scFv domain was fused to the hinge and constant domains of a human IgG1 and to exotoxin A from Pseudomonas aeruginosa lacking domain 1a. This created an immunotoxin that formed a homodimer through disulphide bonds between the hinge regions. Redrawn from12.
