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. 2016 Sep 20;19(9):590–594. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2016.09.05

2.

标志物下降程度与最好疗效、分期及复发类型的关系(Md/Q)

Correlation between decrease of tumor markers (%) and the best efficacy and stageand three types of relapse (Md/Q)

  Item Decreaseof NSE (%) Z/χ2 P Decrease of ProGRP (%) Z/χ2 P Decrease of LDH (%) Z/χ2 P
CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.
The best efficacy 8.386 0.015 12.906 0.002 0.837 0.658
  CR+PR 68.00 (34.90) 77.10 (38.33) 14.11 (25.68)
  SD 53.05 (33.87) 23.51 (80.31) 9.68 (22.96)
  PD 44.45 (110.38) 6.53 (54.22) 16.97 (43.97)
Stage -3.569 < 0.001 -0.348 0.728 -3.430 0.001
  LD 57.28 (36.83) 74.67 (35.84) 10.57 (24.65)
  ED 75.09 (30.26) 70.75 (73.56) 21.19 (34.89)
Types of relapse 1.524 0.467 4.821 0.090 3.469 0.177
  Sensitive relapse 68.55 (38.85) 81.77 (31.66) 9.68 (22.34)
  Drug resistance relapse 65.87 (32.87) 72.48 (62.14) 18.42 (15.09)
  Refractory relapse 74.10 (31.49) 58.31 (63.88) 19.92 (26.34)