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. 2017 Oct 20;20(10):695–702. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2017.10.06

2.

中国肺癌免疫靶向药物研发纵览

Independent research and development of checkpoint inhibitors in China

Category Drug Study progress Approved document time
PD-1: programmed death 1; PD-L1: programmed death-1; CTLA-4: cytotoxic T-lymphocyte-associated protein 4; BTLA-4: B-and T-lymphocyte attenuator-4.
PD-1 SHR-1210 Phase Ⅰb and phase Ⅱ study are ongoing 2016.2
BGB-A317 Phase Ⅰ study is ongoing 2016.9
JS001 Phase Ⅰ study is ongoing 2016.1
IBI308 Phase Ⅰ study is completed 2016.9
GLS-010 Clinical trial application stage 2016.4
PD-L1 KN035 Clinical trial application stage 2016.4
WBP3155 Clinical trial application stage 2016.10
JS003 - -
CTLA-4 KN044 - -
BTLA-4 JS004 - -