2.
小细胞肺癌预后单因素和多因素Cox风险比例模型分析
Univariate and multivariate Cox proportional hazards model analysis of OS for SCLC patients
| Index | Comparison | Univariate | Multivariate | |||
| OR (95%CI) | P | OR (95%CI) | P | |||
| Gender | Male vs Female | 0.722 (0.476-1.095) | 0.125 | |||
| Age | ≥60 yr vs < 60 yr | 1.639 (1.175-2.285) | 0.004 | |||
| Smoking index | ≤400 vs 0 | 1.72 (1.061-2.789) | 0.028 | 1.879 (1.13-3.125) | 0.015 | |
| > 400 vs 0 | 1.377 (0.917-2.069) | 0.123 | ||||
| ECOG | 1 vs 0 | 1.196 (0.776-1.843) | 0.417 | |||
| 2 vs 0 | 3.551 (2.133-5.914) | < 0.001 | 3.202 (1.852-5.539) | < 0.001 | ||
| Stage | ED vs LD | 2.487 (1.793-3.451) | < 0.001 | 1.735 (1.216-2.476) | 0.002 | |
| TNM stage | Ⅲ vs Ⅱ | 1.329 (0.538-3.281) | 0.538 | |||
| Ⅳ vs Ⅱ | 3.308 (1.325-8.258) | 0.010 | ||||
| SVCS | Yes vs No | 2.394 (1.49-3.846) | < 0.001 | 1.988 (1.201-3.291) | 0.008 | |
| Chemotherapy | IC/IP vs CE/EP | 0.956 (0.622-1.471) | 0.838 | |||
| RT | Yes vs No | 0.567 (0.408-0.788) | 0.001 | |||
| TTF-1 | Positive vs Negative | 0.665 (0.472-0.937) | 0.020 | 0.620 (0.439-0.875) | 0.006 | |
| CD56 | Positive vs Negative | 1.124 (0.669-1.887) | 0.660 | |||
| P40 | Positive vs Negative | 0.957 (0.644-1.422) | 0.827 | |||