Skip to main content
. 2018 Apr 16;9(1):235–248. doi: 10.1080/19491034.2018.1456217

Figure 5.

Figure 5.

Anticipation of metabolic complications in lipodystrophic laminopathies. The comparison of the natural history and disease severity in familial forms of lipodystrophic syndromes due to LMNA pathogenic variants reveals similar characteristics and age at onset for lipodystrophy, but an anticipation of metabolic complications over generations. The mean age at onset of each clinical sign is indicated below symbols representing patients from different generations.