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Subgroup Analyses of Moderator Variables for the 3 HRQoL Domains Combined
| Study grouping | Studies, N | Effect size | Z value | P value | Qdf,p |
|---|---|---|---|---|---|
| United States | 2 | –.033 (95% CI, −0.75–0.08) | –1.58 | .110 | 12.85 1, 0.000 |
| Non–United States | 13 | 0.30 (95% CI, 0.12–0.47) | 3.33 | .001 | |
| Older (year 2000–2006) | 4 | –0.24 (95% CI, −0.05–0.03) | –1.64 | .102 | 7.58 1, 0.006 |
| Newer (year 2006–2017) | 11 | 0.39 (95% CI, 0.20–0.57) | 4.06 | .000 |
CI indicates confidence interval; HRQoL, health-related quality of life.
