2.
临床病理特征与OS关系
The relationship between clinicopathologic characteristics and overall survival (OS)
| Clinicopathologic characteristics | Number (%) | HR | 95%CI | P value |
| OS: overall survival; HR: hazard ratio; CI: confidence interval; GGN: ground glass nodule; GGO: ground glass opacity. | ||||
| Gender | 5.090 | 2.105-12.310 | ＜0.001 | |
| Male | 109 (30.53%) | |||
| Female | 248 (69.57%) | |||
| Age | 2.951 | 1.222-7.126 | 0.016 | |
| ≤60 years | 188 (52.66%) | |||
| ＞60 years | 169 (47.34%) | |||
| Smoking history | 5.023 | 2.238-11.273 | ＜0.001 | |
| Yes | 61 (17.09%） | |||
| No | 296 (82.91%) | |||
| Sum of the diameters of the nodes | 8.419 | 2.497-28.394 | 0.001 | |
| ≤3 cm | 317 (88.80%) | |||
| ＞3 cm | 40 (11.20%) | |||
| Diameter of the maximal node | 9.269 | 3.154-27.239 | ＜0.001 | |
| ≤2 cm | 244 (68.35%) | |||
| ＞2 cm | 113 (31.65%) | |||
| Lymph node status | 4.592 | 2.002-10.532 | ＜0.001 | |
| Positive | 38 (10.64%) | |||
| Negative | 319 (89.36%) | |||
| Location | ||||
| Same lobe | 132 (36.98%) | 1 | ||
| Ipsilateral but different lobe | 128 (35.85%) | 2.551 | 0.896-7.264 | 0.079 |
| Bilateral | 97 (27.17%) | 1.549 | 0.491-4.888 | 0.455 |
| Pathological pattern | 0.127 | 0.055-0.293 | ＜0.001 | |
| Same | 331 (92.72%) | |||
| Different | 26 (7.28%) | |||
| Number of the lesions | 0.225 | 0.049-1.025 | 0.054 | |
| 2 | 269 (75.35%) | |||
| ≥3 | 88 (24.65%) | |||
| Pleura status | 22.752 | 7.730-66.965 | ＜0.001 | |
| Positive | 65 (18.21%) | |||
| Negative | 292 (81.79%) | |||
| Imageological characteristics | ||||
| GGN-GGN | 34 (9.52%) | 15.274 | 4.793-48.680 | ＜0.001 |
| GGN-GGO | 92 (25.77%) | 5.394 | 1.660-17.529 | 0.005 |
| GGO-GGO | 231 (64.71%) | 1 | ||
| Surgical method | ||||
| Lobectomy+lobectomy | 138 (38.66%) | 1 | ||
| Lobectomy+limited-resection | 129 (36.13%) | 1.253 | 0.464-3.385 | 0.656 |
| Limited-resection+limited-resection | 90 (25.21%) | 2.079 | 0.760-5.690 | 0.154 |