1.
局限期小细胞肺癌患者临床特征(n=26)
Patient characteristics with limited-stage small cell lung cancer (LS-SCLC) (n=26)
| Clinical Characteristics | Dose level | Total | ||
| Dose level Ⅰ | Dose level Ⅱ | Dose level Ⅲ | ||
| EOCG: Eastern Cooperative Oncology Group; AJCC: American Joint Committee on Cancer. | ||||
| Number of patients | 3 | 3 | 20 | 26 |
| Age (yr) [Median (range)] | 49 (47-56) | 43 (43-51) | 56.6 (30-68) | 52 (30-68) |
| Gender [n (%)] | ||||
| Male | 2 (66.7) | 3 (100) | 15 (75.0) | 20 (76.9) |
| Female | 1 (33.3) | 0 (0) | 5 (25.0) | 6 (23.1) |
| ECOG performance [n (%)] | ||||
| 0 | 2 (66.7) | 2 (66.7) | 13 (65.0) | 17 (65.4) |
| 1 | 1 (33.3) | 1 (33.3) | 7 (35.0) | 9 (34.6) |
| T stage [n (%)] | ||||
| 1 | 0 (0) | 0 (0) | 5 (25.0) | 5 (19.2) |
| 2 | 1 (33.3) | 2 (66.7) | 6 (30.0) | 9 (34.6) |
| 3 | 1 (33.3) | 0 (0) | 1 (5.0) | 2 (7.7) |
| 4 | 1 (33.3) | 1 (33.3) | 8 (40.0) | 10 (38.5) |
| N stage [n (%)] | ||||
| 0 | 0 (0) | 0 (0) | 1 (5.0) | 1 (3.8) |
| 1 | 0 (0) | 1 (33.3) | 3 (15.0) | 4 (15.4) |
| 2 | 2 (66.7) | 2 (66.7) | 11 (55.0) | 15 (57.7) |
| 3 | 1 (33.3) | 0 (0) | 5 (25.0) | 6 (23.1) |
| AJCC stage [n (%)] | ||||
| Ⅱa | 0 (0) | 0 (0) | 3 (15.0) | 3 (11.5) |
| Ⅱb | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Ⅲa | 2 (66.7) | 1 (33.3) | 8 (40.0) | 11 (42.3) |
| Ⅲb | 1 (33.3) | 2 (66.7) | 9 (45.0) | 12 (46.2) |
| Induction chemotherapy [n (%)] | ||||
| Yes | 3 (100) | 1 (33.3) | 16 (80.0) | 20 (76.9) |
| No | 0 (0) | 2 (66.7) | 4 (20.0) | 6 (23.1) |
| Prophylactic cranial irradiation [n (%)] | ||||
| Yes | 2 (66.7) | 1 (33.3) | 15 (75.0) | 18 (69.2) |
| No | 1 (33.3) | 2 (66.7) | 5 (25.0) | 8 (30.8) |