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. 2017 Jun 20;20(6):382–388. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2017.06.03

1.

肺腺癌手术和活检标本中EGFR基因突变率及与年龄性别的关系

Relationship between the EGFR mutation rate and age, gender in lung adenocarcinoma of surgical removal and biopsy specimens

n EGFR χ2 P
Mutation[n(%)] Wild[n(%)]
EGFR: epidermal growth factor receptor.
Surgical removal specimen 163 102(62.58) 61(37.42)
  Gender 4.242 0.039
    Male 56 29(51.79) 27(48.21)
    Female 107 73(68.22) 34(31.78)
  Age(yr) 4.105 0.043
     < 60 70 50(71.43) 20(28.57)
    ≥60 93 52(55.91) 41(44.09)
Biopsy specimen 173 114(65.90) 59(34.10)
  Gender 9.298 0.002
    Male 75 40(53.33) 35(46.67)
    Female 98 74(75.51) 24(24.49)
  Age(yr) > 0.05
     < 60 68 42(61.76) 26(38.24)
    ≥60 105 72(68.57) 33(31.43)