. 2018 May 24;13:1675–1682. doi: 10.2147/COPD.S161225

Table 5.

FEV₁/FVC, FEV₁% predicted, exacerbation frequency, and mMRC in different CCQ categories

Variables	Acceptable CCQ<1	Acceptable for moderate disease 1≤CCQ<2	Instable-severe limited 2≤CCQ<3	Very instable-very severe limited CCQ≥3	P-value
FEV₁/FVC	59.90±15.82^▲,^¶	46.19±12.11^▲,^¶	42.05±12.33^*,^#	37.51±11.52^*,^#	<0.001
FEV₁ % predicted	62.53±21.06^▲,^¶	51.53±18.10^▲,^¶	46.65±18.94^*,^#,^¶	38.34±17.39^*,^#,^▲	<0.001
Exacerbation frequency in the last year	0.10±0.32^#,^▲,^¶	0.49±0.98^*,^▲,^¶	1.26±1.22^*,^#	2.44±1.48^*,^#,^▲	<0.001
mMRC	0.70±0.48^#,^▲,^¶	1.54±0.79^*,^▲,^¶	2.19±0.73^*,^#,^¶	2.68±0.77^*,^#,^▲	<0.001

Notes:

P<0.05 vs CCQ<1;

P<0.05 vs 1≤CCQ<2;

^▲

P<0.05 vs 2≤CCQ<3;

^¶

P<0.05 vs CCQ≥3.

Abbreviations: CCQ, clinical COPD questionnaire; FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; mMRC, modified Medical Research Council dyspnea score.