Table 6.

Score of CAT and CCQ by GOLD grades

Variables	Grade 1, n=30	Grade 2, n=122	Grade 3, n=172	Grade 4, n=48	P-value
CAT	13.80±6.27¶	13.89±5.28▲,¶	15.56±5.61#,¶	19.77±6.70*,#,▲	<0.001
CCQ total	1.76±0.70▲,¶	1.85±0.61▲,¶	2.06±0.69*,#,¶	2.51±0.93*,#,▲	<0.001
CCQ symptom	2.02±0.84¶	2.06±0.76¶	2.16±0.80¶	2.50±1.03*,#,▲	=0.013
CCQ function	1.53±0.81▲,¶	1.70±0.68▲,¶	1.97±0.76*,#	2.53±1.02*,#▲	<0.001
CCQ mental	1.68±1.05	1.62±1.09¶	1.86±1.14	2.18±1.42#	=0.033
Exacerbation frequency	0.37±0.67▲,¶	0.79±1.20¶	1.06±1.31*	1.65±1.41*,#	<0.001

Notes:

^*P<0.05 vs Grade 1;

^#P<0.05 vs Grade 2;

^▲P<0.05 vs Grade 3;

^¶P<0.05 vs Grade 4.

Abbreviations: CAT, COPD Assessment Test; CCQ, clinical COPD questionnaire; GOLD, Global Initiative for Chronic Obstructive Lung Disease.