Table 2.
Genotype frequencies of FGFR2 rs1219648 and PI3KCA rs6443624 single nucleotide polymorphisms in patients and healthy controls
| Genotype | Controls (%) n=389 | Cases (%) n=328 | OR (95% CI) | p-value |
|---|---|---|---|---|
| FGFR2 rs1219648 | ||||
| AA | 224 (57.6) | 167 (50.9) | 1.00 | |
| AG | 146 (37.5) | 127 (38.7) | 1.17 (0.86–1.59) | 0.331 |
| GG | 19 (4.9) | 34 (10.4) | 2.40 (1.32–4.36) | 0.004 |
| AG+GG | 165 (42.4) | 161 (49.1) | 1.31 (0.98–1.76) | 0.074 |
| PI3KCA rs6443624 | ||||
| CC | 97 (24.9) | 58 (17.7) | 1.00 | |
| AC | 189 (48.6) | 150 (45.7) | 1.33 (0.90–1.96) | 0.154 |
| AA | 103 (26.5) | 120 (36.6) | 1.95 (1.28–2.96) | 0.002 |
| AA+AC | 292 (75.1) | 270 (82.3) | 1.55 (1.07–2.23) | 0.019 |