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. Author manuscript; available in PMC: 2018 May 29.
Published in final edited form as: Mol Neurobiol. 2013 Oct 4;49(2):796–807. doi: 10.1007/s12035-013-8562-z

Fig. 1.

Fig. 1

PDI decreases SOD1 monomers as well as multimers. a Lysates from HEK293A cells transfected with SOD1 and PDI were examined by Western blotting under nonreducing conditions. b, c PDI decreased the relative level of mSOD1 (G93A) protein (shown on Y-axis), and the decrease was observed for both monomers (b) and multimers (c). However, the PDI-induced decrease in SOD1 levels was accentuated for SOD1 monomers of both the wild-type and mutant (SOD1: WT wild-type, G93A G93A mutant, Moc mock-transfected). Values are mean + SEM, n =4; *P <0.01, **P <0.001