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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Fertil Steril. 2018 May;109(5):879–887. doi: 10.1016/j.fertnstert.2018.01.029

Table 2.

Fertility treatment outcomes by major depression status and antidepressant use in the female partner.

PHQ-9 < 10
No antidepressant
(N=1359)		 PHQ-9 < 10
On antidepressant
(N=73)		 PHQ-9 ≥ 10
No antidepressant
(N=72)		 PHQ-9 ≥ 10
On antidepressant
(N=16)
N (%) RR N (%) RR N (%) RR N (%) RR
Achieved pregnancy 497 (36.57%) reference 31 (42.47%) 1.13 (0.85 – 1.50) 31 (43.06%) 1.38 (1.07 – 1.78) 6 (37.5%) 0.94 (0.50 – 1.79)
1st trimester miscarriage 110 (22.13%) reference 14 (45.16%) 1.87 (1.18 – 2.99) 5 (16.12%) 0.85 (0.37 – 1.96) 2 (33.33%) 1.40 (0.47 – 4.17)
Live birth 345 (25.39%) reference 17 (23.29%) 0.88 (0.56 – 1.40) 20 (27.78%) 1.22 (0.84 – 1.78) 4 (25%) 0.91 (0.39 – 2.13)
*

RR (95%CI) adjusted for age, income, months trying to conceive, current smoking, study, race

- Denominator for 1st trimester miscarriage = only subjects who conceived

- Denominator for live birth = all subjects