Table 3.
Fertility treatment outcomes by female subject use of antidepressant medication.
| No antidepressant use (N=1484) |
Any antidepressant use (N=90) |
SSRI use (N=57) |
Non-SSRI use (N=25) |
Both SSRI and non-SSRI use (N=8) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N (%) | RR | N (%) | RR | N (%) | RR | N (%) | RR | N (%) | RR | |
| Achieved pregnancy | 539 (36.32%) | reference | 37 (41.11%) | 1.04 (0.80 – 1.37) | 27 (47.37%) | 1.23 (0.91 – 1.65) | 6 (24%) | 0.55 (0.26 – 1.16) | 4 (50%) | 1.27 (0.64 – 2.53) |
| 1st trimester miscarriage | 118 (21.89%) | reference | 16 (43.24%) | 1.92 (1.22 – 3.02) | 11 (40.74%) | 1.73 (1.00 – 3.0) | 4 (66.67%) | 3.45 (1.99 – 5.98) | 1 (25%) | 1.15 (0.19 – 7.06) |
| Live birth | 370 (24.93%) | reference | 21 (23.33%) | 0.84 (0.55 – 1.27) | 16 (28.07%) | 1.04 (0.66 – 1.64) | 2 (8%) | 0.16 (0.02 – 1.08) | 3 (37.5%) | 1.45 (0.60 – 3.52) |
*
RR (95%CI) adjusted for PHQ-9 score, age, income, months trying to conceive, current smoking, study, race
- Denominator for 1st trimester miscarriage = only subjects who conceived
- Denominator for live birth = all subjects