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. 2017 Jul 8;9(37):24653–24671. doi: 10.18632/oncotarget.19065

Figure 5. Kv10.1 and Orai1 are involved in collagen-dependent survival of BC cell lines.

Figure 5

Effect of Kv10.1 or Orai1 silencing on the apoptotic MCF-7 (A) and T-47D cells (B) rate. Cells were starved for 48 h and the apoptosis assay was carried out by annexin V/IP staining, values are reported as mean ± SEM of triplicate experiments, *p<0.05, ANOVA followed by Holm-Sidak post hoc tests. (C-D) Effect of Kv10.1, Orai1 and Kv10.1 + Orai1 (siComb) silencing on MCF-7 (C) and T-47D (D) cell mortality. Cells were starved for 48 h and the mortality was measured by Trypan Blue assay, values are reported as mean ± SEM of triplicate experiments, *p<0.05, ANOVA followed by Holm-Sidak post hoc tests.