Table 5.
Association ADOS subdomain calibrated severity scores (CSS) and the number of radial migration lines (RMLs)
Model I | Model I + IQ/DQ | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
B | 95% CI | β | p | p acorr | B | 95% CI | β | p | p acorr | |||
Total number of RMLs | ||||||||||||
SA domain CSS | 0.10 | 0.04;0.17 | 0.41 | 0.002 | – | 0.155 | 0.06 | − 0.01; 0.12 | 0.23 | 0.080 | – | 0.300 |
RRB domain CSS | 0.09 | 0.02; 0.17 | 0.33 | 0.016 | – | 0.093 | 0.04 | − 0.04; 0.11 | 0.14 | 0.300 | – | 0.255 |
Frontal lobes | ||||||||||||
SA domain CSS | 0.15 | 0.03; 0.27 | 0.33 | 0.017 | 0.061 | 0.091 | 0.06 | − 0.06; 0.18 | 0.14 | 0.296 | 1 | 0.271 |
RRB domain CSS | 0.13 | − 0.00; 0.27 | 0.27 | 0.057 | 0.203 | 0.052 | 0.03 | − 0.10; 0.17 | 0.07 | 0.608 | 1 | 0.243 |
Parietal lobes | ||||||||||||
SA domain CSS | 0.27 | 0.07; 0.47 | 0.35 | 0.010 | 0.037 | 0.107 | 0.15 | − 0.04; 0.35 | 0.20 | 0.110 | 0.394 | 0.293 |
RRB domain CSS | 0.21 | − 0.03; 0.44 | 0.25 | 0.081 | 0.288 | 0.041 | 0.07 | − 0.14; 0.29 | 0.09 | 0.504 | 1 | 0.246 |
Temporal lobes | ||||||||||||
SA domain CSS | 0.20 | − 0.04; 0.44 | 0.23 | 0.101 | 0.359 | 0.034 | 0.10 | − 0.11; 0.32 | 0.12 | 0.343 | 1 | 0.268 |
RRB domain CSS | 0.24 | − 0.03; 0.50 | 0.25 | 0.075 | 0.269 | 0.043 | 0.13 | − 0.10; 0.37 | 0.14 | 0.262 | 0.935 | 0.258 |
Occipital lobes | ||||||||||||
SA domain CSS | 0.87 | 0.29; 1.45 | 0.39 | 0.004 | 0.015 | 0.137 | 0.66 | 0.14; 1.18 | 0.30 | 0.013 | 0.047 | 0.343 |
RRB domain CSS | 0.64 | − 0.03; 1.31 | 0.26 | 0.062 | 0.222 | 0.049 | 0.40 | − 0.20; 1.00 | 0.16 | 0.186 | 0.665 | 0.266 |
n = 52
ADOS Autism Diagnostic Observation Scale, SA social affect, RRB restricted and repetitive behaviors, IQ intelligence quotient, DQ developmental quotient, adjusted R squared model
aMultiple testing correction (3.57 effective tests) applied
Significant associations are highlighted in bold font