Table 3.
The association of serum MMP-9 and MMP-9/TIMP-1 quartiles with ACS at baseline
| OR (95% CI) | p | |||||||
|---|---|---|---|---|---|---|---|---|
| 1st | 2nd | 3rd | 4th | |||||
| ACS | MMP-9 | Model 1 | 1 | 1.92 (1.20–3.08) | 5.62 (3.48–9.08) | 10.37 (6.20–17.35) | < 0.001 | |
| Model 2 | 1 | 1.64 (0.81–3.30) | 4.84 (2.41–9.72) | 5.81 (2.65–12.76) | < 0.001 | |||
| MMP-9/TIMP-1 | Model 1 | 1 | 1.78 (1.12–2.82) | 5.22 (3.25–8.37) | 6.29 (3.87–10.22) | < 0.001 | ||
| Model 2 | 1 | 1.79 (0.87–3.67) | 5.34 (2.61–10.91) | 4.96 (2.37–10.38) | < 0.001 | |||
| UAP | MMP-9 | Model 1 | 1 | 1.81 (0.61–2.30) | 3.72 (2.00–6.94) | 4.49 (2.28–8.85) | < 0.001 | |
| Model 2 | 1 | 0.89 (0.34–2.31) | 3.09 (1.29–7.37) | 3.81 (1.39–10.47) | 0.004 | |||
| MMP-9/TIMP-1 | Model 1 | 1 | 1.29 (0.66–2.52) | 3.76 (1.98–7.13) | 3.75 (1.93–7.26) | < 0.001 | ||
| Model 2 | 1 | 1.08 (0.40–2.89) | 3.18 (1.28–7.89) | 3.89 (1.55–9.74) | 0.005 | |||
| AMI | MMP-9 | Model 1 | 1 | 2.70 (1.50–4.86) | 7.65 (4.25–13.77) | 16.82 (9.13–30.98) | < 0.001 | |
| Model 2 | 1 | 3.01 (1.10–8.27) | 9.05 (3.32–24.62) | 10.97 (3.72–32.35) | < 0.001 | |||
| MMP-9/TIMP-1 | Model 1 | 1 | 2.14 (1.23–3.70) | 6.28 (3.62–10.87) | 8.34 (4.76–14.61) | < 0.001 | ||
| Model 2 | 1 | 3.55 (1.26–10.00) | 11.46 (4.09–32.06) | 8.73 (3.03–25.10) | < 0.001 | |||
Model 1 stratified for age and sex (N = 654); model 2 stratified for age, sex, and adjusted for CRP, cholesterol concentration, and smoking (N = 504)