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EC50 of mutein binding to the antigen calculated using data from Figure 3.
| Variable region of the mutein and type of the antigen | EC50 of mutein binding (nM) | ||||
|---|---|---|---|---|---|
| IgG3 | IgG3_h-1 | IgG3_CH1h-1 | IgG3_CH2-1 | IgG3_CH3-1 | |
| M18 (erythrocytes) | 0.24 ± 0.02 | 0.38 ± 0.01 | 0.61 ± 0.03 | 0.86 ± 0.04 | 0.87 ± 0.07 |
| O10 (erythrocytes) | 0.81 ± 0.01 | 0.88 ± 0.02 | 2.05 ± 0.06 | 9.75 ± 2.04 | 3.60 ± 0.29 |
| O10 (B-trisaccharide conjugated to BSA) | 0.50 ± 0.04 | 0.38 ± 0.02 | 1.15 ± 0.06 | 1.40 ± 0.03 | 0.79 ± 0.06 |
