Table 2.

Risk of type 2 diabetes according to metabolites and diet quality score.

	PC aa C32:1		SM(OH) C22:2		Modified RFS
	HR	p-value	HR	p-value	HR	p-value
Model 1	1.469	<0.001	0.714	<0.001	—	—
Model 2	—	—	—	—	0.795	<0.001
Model 3
PC aa C32:1	1.428	<0.001	—	—	0.837	0.006
SM(OH) C22:2	—	—	0.734	<0.001	0.826	0.003

Hazard Ratios were obtained with cox proportional hazards regression model according to the model adjusted. Basic model: age, sex, area, metabolic equivalent, smoking status, drinking status, household income, education level, and prevalence of hypertension adjusted (data not shown). Model 1: basic model + metabolites adjusted; Model 2: basic model + modified RFS adjusted; Model 3: basic model + metabolites + modified RFS adjusted. The values of metabolites used in this analysis were log-transformed and normalized using z score.