Table 4.
A summary showing the comparison of SNPs found by this paper’s pipeline to four public databases.
| Database or study name | Total SNPs | Total studies or samples | Total SNPs in database shared with this paper target genes | Total positions shared with the database | Total positions not shared with the database |
|---|---|---|---|---|---|
| PlasmoDB | 1,775,395 | 16 studies | 673 | 34 | 11 |
| P. falciparum Community Project | 681,587 | 3,488 samples from 23 countries | 831 | 39 | 6 |
| Pf3K | 944,270 | 2,512 samples from 14 countries | 884 | 30 | 15 |
| Total positions unique to our sequencing data (excluding K13-propeller) | 4b | ||||
| Ménard D et al.a (K13-propeller only) | 108 | 14,037 samples from 59 countries | 108 | 0 | 10 |
| Total positions unique to our sequencing data (including K13-propeller) | 13c | ||||
Data is obtained with flow cell R7.3 and R9.4.
aMénard, D. et al. A worldwide map of Plasmodium falciparum K13-propeller polymorphisms. N. Engl. J. Med. 374, 2453–2464 (2016). bOne mutation in K13 non-propeller region (R101K) is included here due to its significant presence in the clinical samples. cOne synonymous mutation (627A) in K13-propeller region is excluded because it is found in two other databases.