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. 2018 May 29;8:8217. doi: 10.1038/s41598-018-26384-7

Table 8.

Plasma lipid profiles (mean ± SD).

OPP treatment (n = 25) Control treatment (n = 25)
Total cholesterol, TC (mmol/L)
  Day 1 4.99 ± 0.71 4.83 ± 0.74
  Day 30 5.17 ± 0.75 4.97 ± 0.72
  Day 60 4.94 ± 0.701 5.16 ± 0.82
Triacylglycerol, TAG (mmol/L)
  Day 1 1.09 ± 0.69 1.15 ± 0.61
  Day 30 1.14 ± 0.61 1.06 ± 0.54
  Day 60 0.94 ± 0.40 0.97 ± 0.47
HDL-C (mmol/L)
  Day 12 1.36 ± 0.32 1.29 ± 0.30
  Day 30 1.36 ± 0.30 1.31 ± 0.29
  Day 60 1.26 ± 0.26 1.32 ± 0.29
LDL-C (mmol/L)
  Day 1 3.13 ± 0.66 3.01 ± 0.66
  Day 30 3.29 ± 0.77 3.17 ± 0.70
  Day 60 3.25 ± 0.733 3.40 ± 0.79
Total cholesterol/HDL ratio
  Day 1 3.89 ± 1.13 3.93 ± 1.11
  Day 30 4.03 ± 1.22 4.00 ± 1.18
  Day 60 4.10 ± 1.21 4.12 ± 1.24

1Although time × treatment interaction was significant, p = 0.001 (2-factor repeated measures ANOVA) and TC was significantly lower for OPP compared to control treatment (at day 60), based on Wilcoxon signed rank test (p = 0.025), no significant difference of total cholesterol level was found between OPP and control treatments at day 1, 30 and 60 following Bonferroni correction.

2Baseline HDL-C level was significantly different between treatments, p = 0.038 (Wilcoxon signed rank test). The value was further used as covariate in repeated measures. Although the time × treatment analysis was significant, p = 0.011 (2-factor repeated measures ANOVA), no significant difference of HDL-C level was found between treatments at day 30 and 60 based on Wilcoxon signed rank test. Similarly, no significant difference of HDL-C level was found between treatments at day 30 and 60 after Bonferroni correction.

3Although the time × treatment interaction was significant, p = 0.018 (2-factor repeated measures ANOVA) and LDL-C was significantly lower for OPP compared to control treatment (at day 60) based on Wilcoxon signed rank test (p = 0.04), no significant difference of LDL-C level was found between OPP and control treatments at day 1, 30 and 60 following Bonferroni correction.