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. 2018 May 23;9:543. doi: 10.3389/fphar.2018.00543

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Copyright © 2018 Wang, De, Yue, Ma, Cheng, Zhu, Du, Yi, Zhao and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The inhibitory effects on motility, invasion and migration of 4T1 cells. (A) Wound healing images taken after treatment by PTX, PELA-PTX and PELA-PBAE-PTX with PTX dosage of 40 nM for 0 and 48 h, respectively. Representative invasion (B) and migration (C) images of cells treated with respective PTX formulations. Quantitative analysis of the inhibitory effects on cell motility (D), invasion (E) and migration (F) after treatments with different PTX formulations for 24 h. Data were presented as mean ± SD (n = 3). ^∗p < 0.05 vs. control group.