Table 1.
Demographic and clinical characteristics of SCZ and HC.
| Variables | SCZ | HC | P-value |
|---|---|---|---|
| Number | 28 | 21 | |
| Age(years) | 23.9 (5.4) | 28.8 (6.1) | 0.005* |
| Gender (M/F) | 16/12 | 14/7 | 0.498 |
| Education (years) | 12.9(2.0) | 12.9 (3.8) | 1.000 |
| Illness Duration (months) | 15.1 (14.2) | – | – |
| MD (clz eqa) (mg/d) | 384.9 (243.8) | – | – |
| SNPs | |||
| Rs821617 (G+/AA) | 6/22 | 7/14 | 0.350 |
| Rs821616 (Cys+/SerSer) | 9/19 | 6/15 | 0.788 |
| Rs2738880 (G+/AA) | 18/10 | 10/11 | 0.243 |
| Rs1535530 (C+/TT) | 14/14 | 11/10 | 0.869 |
| PANSS total score | 85.7 (19.9) | – | – |
| PANSS positive score | 17.8 (6.5) | – | |
| PANSS negative score | 21.0 (6.2) | – | |
| PANSS general score | 38.9 (9.4) | – | |
Data are given as mean (standard deviation)
*
P < 0.05.
a
clz eq, chlorpromazine equivalents; MD, medication dose; SCH, schizophrenia; HC, healthy controls; PANSS, positive and negative syndrome scale.