Table 2.

Main effect and interactive effects across diagnosis and genotypes.

Contrast	Cluster size	P-value	Effect size (partial η2)	MNI coordinates			Region
				x	y	z
MAIN EFFECT OF DIAGNOSIS
	112	1.00E−06	0.40	−15	−15	12	THA (VLN)
	55	1.40E−05	0.34	12	−12	9	THA (VLN)
MAIN EFFECT OF GENOTYPES
rs821617	31	1.80E−05	0.33	42	15	54	MFG
rs821616	69	2.00E−06	0.39	−30	36	48	MFG
INTERACTION: GENOTYPE × DIAGNOSIS
rs821617	101	3.00E−05	0.33	3	−75	51	PCUN
	53	4.40E−05	0.32	42	−81	0	MOG
	115	2.60E−04	0.26	−3	−93	6	CAL
	41	2.90E−05	0.33	24	−9	9	PUTA
	38	2.90E−05	0.33	21	−3	−6	PALL
	91	8.10E−05	0.30	−33	−18	45	PreCG
	116	2.45E−04	0.27	33	−33	45	PostCG
rs821616	35	2.60E−05	0.33	−60	−51	9	MTG (extending to STG)
	40	2.30E−05	0.34	−39	−42	63	PostCG
rs2738880	63	1.80E−05	0.35	−51	−54	−6	ITG

AlphaSim correction with a combined statistical thresholds of P < 0.005 at voxel level and P < 0.001 at cluster level. THA, thalamus; MFG, middle frontal gyrus; PCUN, precuneus; MOG, middle occipital gyrus; CAL, calcarine; PUTA, putamen; PALL, pallidum; ITG, inferior temporal gyrus; STG, MTG, superior/middle temporal gyrus; PreCG, Pre-central gyrus; PostCG, Post-central gyrus; VLN, Ventral Lateral Nucleus.