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. 2018 May 29;8:8248. doi: 10.1038/s41598-018-26607-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Individual profiles of miRNAs showing switches in arm counts at early and adult stages. X-axis represents 3p miRNA mapped raw read counts (log₂) and Y-axis represents 5p miRNA mapped raw read counts (log₂). Diagonal line represents same expression rates from 5p and 3p. Data series on the right side of the line shows greater proportion of 5p over 3p, while data series on the left side of the line shows a greater proportion of 3p over 5p.Threshould (dashed red line) represents Fold change ≥2 or ≤−2.