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. 2018 May 29;8:8196. doi: 10.1038/s41598-018-26399-0
Parameter Meaning Estimated Value Units
kmS1 Permeability of the cell membrane to acetoacetyl-CoA 10−4 cm/s
kmS2 Permeability of the cell membrane to HMG-CoA 10−4 cm/s
kcatCDE Maximum reaction rate of a HMGS active site 1.8385 1/s
NCDE Number of HMGS enzymes per cell 5 × 10563 Per cell
KMCDE Michaelis-Menten constant of HMGS 586 μM
kcatPQ Maximum reaction rate of a HMGR active site 0.02387 1/s
KMPQ Michaelis-Menten constant of HMGR 1 × 10287 μM
NPQ Number of HMGR enzymes per cell 5 × 10563 Per cell