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. 2018 May 29;9(6):655. doi: 10.1038/s41419-018-0688-5

Fig. 1. MPT0G211 exhibited potent HDAC6 inhibition.

Fig. 1

a The structure of MPT0G211. b, c SH-SY5Y or Neuro-2a cells were treated with the indicated concentrations of MPT0G211, ACY-1215, or SAHA for 24 h, and the whole-cell lysate was subjected to western blotting with the indicated antibodies. d SH-SY5Y and Neuro-2a cells were incubated for 24 h with or without the indicated concentrations of MPT0G211 or ACY-1215. Cell viabilities were determined by MTT assay. The results represent the mean ± SEM of three independent experiments; *p < 0.05, **p < 0.01 and ***p < 0.001 compared with controls