TABLE 3 .
Genes deleted from mc28245 and mc28250
| Gene | Coordinates | Cla | Product |
|---|---|---|---|
| Rv1867 | 2115764–2117248 | 1 | Conserved hypothetical protein |
| Rv1868 | 2117347–2119446 | 10 | Conserved hypothetical protein |
| Rv1869c | 2119460–2120695 | 7 | Probable reductase |
| Rv1870c | 2120795–2121430 | 10 | Conserved hypothetical protein |
| Rv1871c | 2121495–2121884 | 10 | Conserved hypothetical protein |
| lldD2 | 2121907–2123151 | 7 | Possible l-lactate dehydrogenase (cytochrome) |
| Rv1873 | 2123174–2123611 | 10 | Conserved hypothetical protein |
| Rv1874 | 2123684–2124370 | 10 | Hypothetical protein |
| Rv1875 | 2124381–2124824 | 10 | Conserved hypothetical protein |
| bfrA | 2125340–2125819 | 7 | Probable bacterioferritin |
| Rv1877 | 2125904–2127967 | 3 | Probable conserved integral membrane protein |
| glnA3 | 2128022–2129374 | 7 | Probable glutamine synthetase |
| Rv1879 | 2129377–2130513 | 10 | Conserved hypothetical protein |
| cyp140 | 2130541–2131857 | 7 | Probable cytochrome P450 140 |
| lppE | 2131907–2132329 | 3 | Possible conserved lipoprotein |
| Rv1882c | 2132370–2133203 | 7 | Probable short-chain-type dehydrogenase |
| Rv1883c | 2133231–2133692 | 10 | Conserved hypothetical protein |
| rpfC | 2133731–2134261 | 3 | Probable resuscitation-promoting factor |
| Rv1885c | 2134273–2134872 | 7 | Conserved hypothetical protein |
| fbpB | 2134890–2135867 | 1 | Secreted antigen 85-B |
| Rv1887 | 2136258–2137400 | 10 | Hypothetical protein |
| Rv1888c | 2137519–2138079 | 10 | Possible transmembrane protein |
| Rv1888A | 2138444–2138617 | 3 | Conserved hypothetical protein |
| Rv1889c | 2138661–2139017 | 10 | Conserved hypothetical protein |
| Rv1890c | 2139076–2139687 | 10 | Hypothetical protein |
| Rv1891 | 2139741–2140148 | 10 | Conserved hypothetical protein |
| Rv1892 | 2140165–2140476 | 3 | Probable membrane proteins |
| Rv1893 | 2140486–2140704 | 10 | Conserved hypothetical protein |
| Rv1894c | 2140739–2141869 | 10 | Conserved hypothetical protein |
| Rv1895 | 2142521–2143675 | 7 | Possible dehydrogenase |
| Rv1896c | 2143535–2144446 | 10 | Conserved hypothetical protein |
| Rv1897c | 2144451–2144882 | 10 | Conserved hypothetical protein |
| Rv1898 | 2144940–2145248 | 10 | Conserved hypothetical protein |
| lppD | 2145214–2146245 | 3 | Possible lipoprotein |
| lipJ | 2146245–2147633 | 7 | Probable lignin peroxidase |
| cinA | 2147662–2148954 | 0 | Probable CinA-like protein |
| nanT | 2149006–2150274 | 3 | Probable sialic acid transport membrane proteins |
| Rv1903 | 2150364–2150768 | 3 | Probable conserved membrane proteins |
| Rv1904 | 2150954–2151385 | 10 | Conserved hypothetical protein |
| aao | 2151433–2152395 | 7 | Probable d-amino acid oxidase |
| Rv1906c | 2152425–2152895 | 10 | Conserved hypothetical protein |
| Rv1907c | 2153235–2153882 | 10 | Hypothetical protein |
| katG | 2153889–2156111 | 0 | Catalase-peroxidase-peroxynitritase T |
| furA | 2156149–2156601 | 9 | Ferric uptake regulation protein |
| Rv1910c | 2156706–2157299 | 3 | Probable exported protein |
| lppC | 2157382–2157987 | 3 | Probable lipoprotein |
| fadB5 | 2158087–2159091 | 1 | Possible oxidoreductase |
| Rv1913 | 2159191–2159943 | 10 | Conserved hypothetical protein |
| Rv1914c | 2159921–2160328 | 10 | Hypothetical protein |
| aceAa | 2160463–2161566 | 7 | Probable isocitrate lyase (first part) |
| aceAb | 2161566–2162762 | 7 | Probable isocitrate lyase (second part) |
| PPE34 | 2162932–2167311 | 6 | PPE family protein |
| PPE35 | 2167649–2170612 | 6 | PPE family protein |
a
Cl, classification, based on the TubercuList website (http://genolist.pasteur.fr/TubercuList/), with the following categories: 0, virulence, detoxification, adaptation; 1, lipid metabolism; 3, cell wall and cell processes; 6, PE/PPE; 7, intermediary metabolism and respiration; 9, regulatory proteins; 10, conserved hypothetical proteins.