Table 1.

Pharmacokinetic parameters of TCF in Carassius auratus gibelio (n = 3).

Parameter	Unit	Plasma			Liver
		0.5 mg/kg	1 mg/kg	2 mg/kg	0.5 mg/kg	1 mg/kg	2 mg/kg
Cmax	μg/g	9.793	11.715	13.208	20.495	24.912	45.058
Tmax	h	5.37	4.75	3.56	3.69	2.65	4.45
T1/2alpha	h	5.554	4.169	5.143	2.302	0.123	2.076
T1/2Ka	h	2.796	4.681	3.941	2.535	1.808	4.461
Kel	h	0.133	0.758	1.102	0.796	0.583	0.208
CLs	L/h⋅kg	6.520	10.229	18.664	5.158	10.494	7.088
AUC	μg/L⋅h	153.363	195.523	214.317	193.884	190.592	564.314
Ka	1/h	0.248	0.148	0.176	0.273	0.383	0.155

Cmax, the peak concentration in plasma; Tmax, the time point of the drug’s maximum plasma concentration; T_{1/2 alpha}, distribution half-life of the drug; T_{1/2 Ka}, absorption half-life of the drug; Kel, elimination rate constant from the central compartment; CLs, total body clearance; AUC, Area under the drug concentration-time curve from the time zero to last time point; Ka, absorption rate constant.