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. 2018 May 28;17:1533034618775509. doi: 10.1177/1533034618775509

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Exogenetic overexpression of miR-199a inhibits cell proliferation, migration, and invasion but induces apoptosis in CRC cells. A, Restoration of miR-199a inhibits SW480 or LS174T cell proliferation. B, Overexpression of miR-199a impedes the colony formation ability of SW480 cells. C, Exogenetic overexpression of miR-199a markedly reduces the migration of SW480 or LS174T cells. D, Exogenetic overexpression of miR-199a significantly reduces the invasiveness of SW480 or LS174T cells. E, miR-199a overexpression induces apoptosis in SW480 cells. **P < .01. CRC indicates colorectal cancer; miR-199a, microRNA-199a.