Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 28;17:1533034618775509. doi: 10.1177/1533034618775509

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — MicroRNA-199a inhibits tumor growth in vivo. A, Stable transfection of miR-199a into SW480 cells results in decreased growth and tumor weight. B, immunohistochemical staining demonstrates that the tumors originating from LV-miR-199a cells have decreased expression of Ki-67 and ROCK1 compared with that from LV-Ctrl cells. C, The inverse correlation between the levels of miR-199a and mRNA expression of ROCK1 in CRC tissues (n = 40). *P < .05. CRC indicates colorectal cancer; mRNA, messenger RNA; miR-199a, microRNA-199a; ROCK1, Rho-associated coiled coil-containing protein kinase 1