Table 2.
Total |
Healed |
||||
---|---|---|---|---|---|
DFU clinical characteristics | n | n | % | p-Value | Odds ratio (95% confidence interval) |
Dorsal diabetic foot ulcer (dorsum, toes and digital amputation sites) | 153 | 118 | 77 | 0.03a | – |
≥2 diabetic foot ulcers | 66 | 46 | 70 | 0.6 | – |
Diabetic foot ulcer duration ≥ 1 month | 118 | 86 | 73 | 0.8 | – |
Loss of pain sensation | 218 | 161 | 74 | 0.6 | – |
Monophasic Doppler signal | 74 | 45 | 63 | 0.004b | 0.43 (0.2–0.8) |
Neuroischaemic/ischaemic DFU classification | 120 | 77 | 64 | 0.02c | 0.49 (0.29–0.81) |
Positive probe-to-bone | 66 | 41 | 62 | 0.02d | 0.52 (0.29–0.92) |
Positive X-ray | 60 | 37 | 62 | 0.03e | 0.67 (0.3–1.5) |
Osteomyelitis | 90 | 58 | 64 | 0.05f | 0.60 (0.36–1.01) |
Positive bacterial growth | 129 | 90 | 70 | 0.4 | – |
Methicillin-resistant Staphylococcus aureus | 11 | 8 | 73 | 0.4 | – |
p-value related to clinical factors which may or may not affect DFU healing (p = 0.05 or less shows significance).
aCompared to plantar and calcaneal ulcers.
bCompared to biphasic and triphasic Doppler pulses.
cCompared to neuropathic DFU.
dCompared to negative probe-to-bone.
eCompared to negative radiological findings.
fCompared to DFU not complicated by osteomyelitis.