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. 2018 May 23;6(10):e13707. doi: 10.14814/phy2.13707

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© 2018 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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RS‐102895 does not improve renal fibrosis and macrophage infiltration in the unilateral IRI mice model. (A) Immunohistochemistry of F4/80. Macrophage infiltration by immunohistochemistry of F4/80 (arrows) did not reduce by RS‐102895 compared with the vehicle group (×400, scale bar = 50 μm). (B) Immunohistochemistry of CD206. M2 macrophage infiltration did not reduce by RS‐102895 compared with the vehicle group (×400, scale bar = 50 μm). (C) Masson trichrome staining. RS‐102895 did not improve renal fibrosis (×200, scale bar = 100 μm, vehicle, RS‐102895; n = 6).