Skip to main content
. 2018 Feb 19;163(2):466–477. doi: 10.1093/toxsci/kfy040

Figure 4.

Figure 4.

SPM precursor/SPM administration prior to O3 exposure increases pulmonary 14-HDHA and 17-HDHA levels. 1 h prior to filtered air (FA) or 1 ppm O3 exposure (3 h) mice were i.p. injected with 14-HDHA, 17-HDHA, and PDX. 24 h following exposure, A, lung and B, spleen tissue was harvested for specialized pro-resolving mediator (SPM) analysis via LC-MS/MS. *p < .05; **p < .01; n = 5–6 per group.