Table 1.
Essential laboratory parameters
| Characteristic | IV.6 –index case | IV.4 sister |
|---|---|---|
| Age (years) | 51 | 55 |
| Gender | Male | Female |
| Blood counts | ||
| WBC (4.0‐10.5×103/μL) | 7.8 | 9.5 |
| Absolute neutrophil count (2‐6×103/μL) | 4.92 | 6.29 |
| Absolute lymphocyte count (2‐6×103/μL) | 1.96 | 2.63 |
| Monocyte count (0.06‐0.12×103/μL) | 0.55 | 0.47 |
| Hg (11.1‐14.6 g/dL) | 14.7 | 13.2 |
| Platelets (140‐400×103/μL) | 165 | 217 |
| PT (12.2‐14.9 s) | 13.8 | 13.4 |
| PTT (22.2‐35.5 s) | 28.7 | 31.2 |
| Fibrinogen level (139‐482 mg/dL) | 261 | 307 |
| D‐Dimer (<0.49 mg/L FEU) | 0.3 | 0.3 |
| Platelet aggregation assay | ||
| ADP | ||
| 10 μmol/L | 6% | 2% |
| 2 μmol/L | 0% | 1% |
| Collagen | ||
| 4 μg/mL | 1% | 11% |
| 1 μg/ml | 0% | 8% |
| TRAP | ||
| 14‐40 μmol/L | 68% | 75% |
| 8 μmol/L | 72% | 80% |
| PMA | ||
| 10 μmol/L | 75% | 78% |
| 2 μmol/L | 78% | 78% |
| Epinephrine 10 μmol/L | 2% | NA |
| Arachidonic acid 0.5 mmol/L | 0% | NA |
ADP, adenosine diphosphate; Hg, hemoglobin; PMA, phorbol 12‐myristate 13‐acetate; PT, prothrombin time; PTT, partial thromboplastin time; TRAP, thrombin receptor activating peptide.