Table 1.

Clinical and laboratory characteristics of APS patients and Anti‐β2GPI samples

Patient	Clinical characteristics	APL Assays at time of lab draw (Range) Normal range = 0.0–14.9 GPL
APS155	APS Lower extremity deep venous thrombosis (DVT) (2 years prior to blood draw) Non‐acute state at time of draw Medications wafarin	dRVVT (+) Anti‐β2GPI IgA – 5.5 Anti‐β2GPI IgM – 21.4 Anti‐β2GPI IgG – 49.2 Anti‐cardiolipin IgA – n/a Anti‐cardiolipin IgG – >100 Anti‐cardiolipin IgM – 30.2
APS698	APS Systemic Lupus Erythematosus Lower extremity DVT (1 year prior to blood draw) Non‐acute state at time of draw Medications warfarin	dRVVT (+) Anti‐β2GPI IgA – <4 Anti‐β2GPI IgM – 13.2 Anti‐β2GPI IgG – 25 Anti‐cardiolipin IgA – n/a Anti‐cardiolipin IgG – 22.2 Anti‐cardiolipin IgM – 25.7
APS25	APS Multiple PE (2 days prior to draw) S/p thromboendoarterectomy Acute presentation of thrombosis Medications Subtherapeutic on warfarin at the time of draw; on unfractionated heparin	dRVVT (+) Anti‐β2GPI IgA – <4 Anti‐β2GPI IgM – <4 Anti‐β2GPI IgG – 86.5 Anti‐cardiolipin IgA – negative Anti‐cardiolipin IgG – >100 Anti‐cardiolipin IgM – n/a
APS203	Catastrophic antiphospholipid syndrome (sentinel episode three years prior to lab draw) Non‐acute state at time of draw Medications warfarin	dRVVT (+) Anti‐β2GPI IgA – n/a Anti‐β2GPI IgM – n/a Anti‐β2GPI IgG – 0.19 Anti‐cardiolipin IgA – negative Anti‐cardiolipin IgG – negative Anti‐cardiolipin IgM – negative