Fig. 5.

Use of WGA and NGS for chromosome assessment in individual blastocysts originating from young and reproductively aged female. A) Blastocysts derived after IVM and IVF were used for sequencing. A representative blastocyst is shown. Representative sequencing plots of euploid (B) and aneuploid blastocysts (C and D) are shown. Aneuploidy is due to a gain of 1 copy of chromosome 13 (C) and a gain of 1 copy of chromosome 8 (D). *Chromosomes with an abnormal copy number indicative of aneuploidy.