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. 2017 Dec 29;15:284–296. doi: 10.1016/j.redox.2017.12.013

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Differentially expressed miRNAs in heart tissues of rats induced by DOX based on microarrays assay. (A) Hierarchical clustering analysis of the differentially expressed miRNAs between DOX and control samples in rats. (B) Validation of the eight differentially expressed miRNAs in rats caused by DOX based on real-time PCR assay. (C) A schematic diagram used to search the target genes of miRNAs in three databases. (D) Prediction of the target genes of miR-140-5p screened by the database. All data are expressed as the mean ± SD (n = 5). *p < 0.05, **p < 0.01 compared with control group.