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. 2017 Dec 29;15:284–296. doi: 10.1016/j.redox.2017.12.013

Fig. 9.

Fig. 9

MiR140-5p agomir or antagomir adjusts Nrf2 and Sirt2 signaling pathwaysin vivo. (A) The levels of miR-140-5p in DOX-treated mice after administered with agomir or antagomir of miR-140-5p. (B) The expression level of Sirt2 in DOX-treated mice after administered with agomir or antagomir of miR-140-5p. (C) The expression levels of Nrf2, keap1, HO-1, NQO1, Gst, GCLM, Sirt2 and FOXO3a in DOX-treated mice after administered with agomir or antagomir of miR-140-5p. All data are expressed as the mean ± SD (n = 5). **p < 0.01 compared with agomir NC group; ##p < 0.05 compared with antagomir NC group.