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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Child Psychol Psychiatry. 2017 Dec 2;59(6):650–658. doi: 10.1111/jcpp.12843

Figure2. Association of activation of the ventral striatal activation during Monetary Incentive Delay Task and lifetime binge drinking in adolescents (N=393) and interaction with OPRL1 methylation.

Figure2

Significant interaction between OPRL1 methylation and the left VS activation (p= 0.007, pcorrected=0.014) while the interaction was only a trend in the right VS (p=0.030, pcorrected=0.060). Methylation values in panel A and B are separated into low and high methylation using a median slip. Coronal section shows methylation differences in right and left ventral activation during reward anticipation (xyz: ±9, 11, −2) (panel C and D).