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Adjusted hazard ratios for insulin initiation by number of diabetes complications. Diabetes complications included in this analysis are cardiovascular disease, chronic kidney disease, diabetic neuropathy, and diabetic retinopathy. Hazard ratios are fully adjusted (model 3) except for the specified diabetes complications. 95% Confidence intervals for the hazard ratios of 1, 2, and 3+ diabetes complications are (0.89–1.20), (1.05–1.48), and (1.34–2.14), respectively.
