Skip to main content
. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Neuropharmacology. 2018 Mar 23;135:431–443. doi: 10.1016/j.neuropharm.2018.03.019

Figure 1. Cocaine regulates innate immune responses in a dose dependent manner in astrocytes.

Figure 1

Normal human astrocytes (NHA) were treated with increasing doses of cocaine (0-10 μM) in parallel to untreated NHA for 24 hr. IL6 (A), IL8 (B), IFNβ1 (C) and ISG15 (D) mRNA levels were analyzed following cocaine treatments. Statistical analyses were performed using GraphPad Prism V6.0 with one-way ANOVA and Tukey’s post-hoc analysis for multiple comparisons. p values <0.05 were considered statistically significant and data represent means +/− SEM. Representative graphs are shown from a minimum of three independent astrocyte experiments each tested and analyzed in a minimum of triplicate technical determinations. (**p<0.01, ***p<0.001)