Table 1.
Model | df | AIC | BIC | logLik | Test | L.Ratio | p-value | |
---|---|---|---|---|---|---|---|---|
Acquisition of methamphetamine self-administration | ||||||||
| ||||||||
Baseline Model | 1 | 6 | 821.06 | 835.36 | −404.53 | |||
Adding Session Factor | 2 | 7 | 822.63 | 839.31 | −404.32 | 1 vs 2 | 0.43 | 0.51 |
Adding Lever Factor | 3 | 8 | 699.43 | 718.48 | −341.71 | 2 vs 3 | 125.21 | 0.00 |
Adding Session × Lever | 4 | 9 | 699.51 | 720.95 | −340.76 | 3 vs 4 | 1.92 | 0.17 |
| ||||||||
The effect of NAC on responding for methamphetamine | ||||||||
| ||||||||
Baseline Model | 1 | 5 | 321.66 | 328.99 | −155.83 | |||
Adding Dose Factor | 2 | 8 | 327.03 | 338.76 | −155.52 | 1 vs 2 | 0.63 | 0.89 |
Adding Activity Factor | 3 | 9 | 328.54 | 341.73 | −155.27 | 2 vs 3 | 0.49 | 0.48 |
Adding Dose × Activity | 4 | 12 | 321.23 | 338.82 | −148.62 | 3 vs 4 | 13.30 | 0.00 |
| ||||||||
The effect of NAC on methamphetamine-triggered reinstatement | ||||||||
| ||||||||
Baseline Model | 1 | 5.00 | 259.53 | 265.42 | −124.76 | |||
Adding Dose Factor | 2 | 8.00 | 262.67 | 272.09 | −123.33 | 1 vs 2 | 2.86 | 0.41 |
Adding Activity Factor | 3 | 9.00 | 261.42 | 272.02 | −121.71 | 2 vs 3 | 3.25 | 0.07 |
Adding Dose × Activity | 4 | 12.00 | 264.08 | 278.22 | −120.04 | 3 vs 4 | 3.34 | 0.34 |