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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Neuropharmacology. 2018 Mar 28;135:487–495. doi: 10.1016/j.neuropharm.2018.03.021

Table 1.

Statistical output from Experiment 1.

Model df AIC BIC logLik Test L.Ratio p-value
Acquisition of methamphetamine self-administration

Baseline Model 1 6 821.06 835.36 −404.53
Adding Session Factor 2 7 822.63 839.31 −404.32 1 vs 2 0.43 0.51
Adding Lever Factor 3 8 699.43 718.48 −341.71 2 vs 3 125.21 0.00
Adding Session × Lever 4 9 699.51 720.95 −340.76 3 vs 4 1.92 0.17

The effect of NAC on responding for methamphetamine

Baseline Model 1 5 321.66 328.99 −155.83
Adding Dose Factor 2 8 327.03 338.76 −155.52 1 vs 2 0.63 0.89
Adding Activity Factor 3 9 328.54 341.73 −155.27 2 vs 3 0.49 0.48
Adding Dose × Activity 4 12 321.23 338.82 −148.62 3 vs 4 13.30 0.00

The effect of NAC on methamphetamine-triggered reinstatement

Baseline Model 1 5.00 259.53 265.42 −124.76
Adding Dose Factor 2 8.00 262.67 272.09 −123.33 1 vs 2 2.86 0.41
Adding Activity Factor 3 9.00 261.42 272.02 −121.71 2 vs 3 3.25 0.07
Adding Dose × Activity 4 12.00 264.08 278.22 −120.04 3 vs 4 3.34 0.34