Table 2.
Model | df | AIC | BIC | logLik | Test | L.Ratio | p-value | |
---|---|---|---|---|---|---|---|---|
Acquisition of methamphetamine self-administration | ||||||||
| ||||||||
Baseline Model | 1 | 6 | 1509.63 | 1527.28 | −748.82 | |||
Adding Session Factor | 2 | 7 | 1511.54 | 1532.13 | −748.77 | 1 vs 2 | 0.09 | 0.77 |
Adding Lever Factor | 3 | 8 | 1373.14 | 1396.67 | −678.57 | 2 vs 3 | 140.40 | 0.00 |
Adding Session × Lever | 4 | 9 | 1375.06 | 1401.54 | −678.53 | 3 vs 4 | 0.08 | 0.78 |
| ||||||||
The effect estrous on responding for methamphetamine (prior to dose-effect phase) | ||||||||
| ||||||||
Baseline Model | 1 | 4 | 1372.54 | 1384.31 | −682.27 | |||
Adding Estrous Factor | 2 | 5 | 1373.56 | 1388.27 | −681.78 | 1 vs 2 | 0.98 | 0.32 |
| ||||||||
The effect of bupropion on responding for methamphetamine | ||||||||
| ||||||||
Baseline Model | 1 | 5 | 436.99 | 445.43 | −213.49 | |||
Adding Dose Factor | 2 | 8 | 419.57 | 433.08 | −201.79 | 1 vs 2 | 23.42 | 0.00 |
Adding Activity Factor | 3 | 9 | 407.78 | 422.98 | −194.89 | 2 vs 3 | 13.79 | 0.00 |
Adding Dose × Activity | 4 | 12 | 410.90 | 431.17 | −193.45 | 3 vs 4 | 2.88 | 0.41 |
| ||||||||
The effect estrous on responding for methamphetamine (after dose-effect phase) | ||||||||
| ||||||||
Baseline Model | 1 | 4 | 614.79 | 623.43 | −303.40 | |||
Adding Estrous Factor | 2 | 5 | 616.65 | 627.44 | −303.32 | 1 vs 2 | 0.15 | 0.70 |
| ||||||||
The effect of bupropion on methamphetamine-triggered reinstatement | ||||||||
| ||||||||
Baseline Model | 1 | 5 | 301.20 | 307.29 | −145.60 | |||
Adding Dose Factor | 2 | 9 | 289.33 | 300.30 | −135.67 | 1 vs 2 | 19.87 | 0.00 |
Adding Activity Factor | 3 | 10 | 288.57 | 300.76 | −134.29 | 2 vs 3 | 2.76 | 0.10 |
Adding Dose × Activity | 4 | 14 | 291.73 | 308.80 | −131.87 | 3 vs 4 | 4.84 | 0.30 |